All Events
The Panama Railroad company completes a line between the Atlantic and the Pacific, providing America's first transcontinental link
Rudolf Virchow shows that sickness derives from the failure of individual cells, causing him to be known as the father of pathology
The first edition of Walt Whitman's Leaves of Grass is published anonymously, at his own expense, and contains just 12 poems
David Livingstone, moving down the Zambezi, comes upon the Victoria Falls

John Everett Millais marries Effie Gray, previously the wife of John Ruskin

English artist William Simpson sends sketches from the Crimea which achieve rapid circulation in Britain as tinted lithographs
Liberal leaders Juan Alvarez and Ignacio Comonfort launch a political programme in Mexico that becomes know simply as 'the Reform'
The Christian Socialism of F.D. Maurice and others is mocked by its opponents as 'muscular Christianity'
An Ethiopian baron usurps the throne and proclaims himself emperor, as Theodore II
Longfellow publishes his American Indian epic, The Song of Hiawatha, in an irresistibly catchy metre
The Christmas issue of the Illustrated London News includes chromolithographs, introducing the era of colour journalism
After a siege of nearly a year the Russians abandon Sebastopol, but the Turkish alliance is too exhausted to pursue the conflict
Tennyson publishes a long narrative poem, Maud, a section of which ('Come into the garden, Maud') becomes famous as a song

English author Anthony Trollope publishes The Warden, the first in his series of six Barsetshire novels
The treaty of Paris ends the Crimean War, limiting Russia's special powers in relation to Turkey
The first Neanderthal man to be discovered is unearthed by quarry workers in the Neander valley, near Düsseldorf
Abolitionist John Brown presides over the lynching of five pro-slavery men at Pottawatomie in Kansas
An American adventurer, William Walker, wins control of the government in Nicaragua and for a year rules as president
G.H. Lewes encourages Marian to try her hand at fiction and her first story, 'The Sad Fortunes of the Reverend Amos Barton' is successfully published

Victoria and Albert complete their fairy-tale castle at Balmoral, adding greatly to the nation's romantic view of Scotland
Gustave Flaubert publishes Madame Bovary, a novel of frustrated romanticism in a provincial French context
English chemist William Henry Perkin accidentally creates the first synthetic die, aniline purple (now known as mauve)
An incident aboard the Arrow, flying a British flag, gives the British the pretext to launch the Second Opium War
Democrat candidate James Buchanan wins the US presidential election, defeating Republican John C Fr&eqacute;mont
The Kneller Hall Training School closes.