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| c. 1465 |
| | | The Sicilian artist Antonello da Messina adopts the Flemish technique of painting in oils | |
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| 1466 |
| | | In the treaty of Torun the Teutonic knights finally cede Prussia to Poland | |
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| 1466 |
| | | The Portuguese settlers on the Cape Verde islands are granted a monopoly on the new slave trade | |
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| 1467 |
| | | Sir John Saye, Chancellor of the Exchequer to Edward IV, becomes the first recorded resident of Barn Elms, the manor house of Barnes | |
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| 1468 |
| | | Skanderbeg dies and Albania becomes fully absorbed into the Ottoman empire | |
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| c. 1468 |
| | | Jerome van Aken works almost exclusively in his native s' Hertogenbosch, from which he derives the name Hieronymus Bosch | |
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| 1469 |
| | | Thomas Malory, in gaol somewhere in England, compiles Morte d'Arthur – an English account of the French tales of King Arthur | |
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| 1469 |
| | | The Orkneys and Shetlands come into the possession of James III of Scotland with the dowry of Margaret of Denmark | |
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| 1469 |
| | | The marriage of Ferdinand and Isabella unites the crowns of Aragon and Castile, creating virtually a unified Spain | |
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| 1470 |
| | | The first Italian printing press is set up in Venice, which soon rivals Germany for the quality of its printing | |
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