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| 1769 |
| | | Franciscan missionary Junipero Serra begins work at San Diego de Cala, the first of his nine California missions | |
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| 1773 |
| | | Responding to pressure from the Catholic monarchs of Europe, Clement XIV abolishes the Jesuit Order | |
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| 1774 |
| | | The treaty of Kuchuk Kainarji grants Russia special rights in relation to the Christian Holy Places under Ottoman control | |
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| 1774 |
| | | Illiterate visionary Ann Lee, leader of an English sect, the 'Shaking Quakers', crosses the Atlantic to spread the word | |
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| 1775 |
| | | Talleyrand begins an extremely varied career by becoming an abbot at the age of twenty-one | |
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| c. 1780 |
| | | In developing the Haskalah, the German philosopher Moses Mendelssohn reconciles Judaism and the Enlightenment | |
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| 1781 |
| | | Joseph II passes an Edict of Toleration, for the first time allowing Protestant worship in Habsburg territories | |
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| 1781 |
| | | Ann Lee leads her Shaker colleagues in a missionary tour of New England lasting two years | |
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| c. 1790 |
| | | A second great revivalist movement sweeps northeast America, inspired by the earlier example of Jonathan Edwards | |
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| 1795 |
| | | Thomas Paine publishes his completed Age of Reason, an attack on conventional Christianity | |
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