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1536
William Tyndale is captured in Antwerp, condemned as a heretic and strangled at the stake
1543
Flemish anatomist Andreas Vesalius publishes a seven-volume work which for the first time lays bare human anatomy
1556
Charles V abdicates, handing the Netherlands and Spain to his son Philip and the title of Holy Roman emperor to his brother Ferdinand
c. 1565
Pieter Brueghel the Elder depicts biblical events taking place among the peasants of the Netherlands countryside
Pieter Brueghel the Elder
Adoration of the Kings
(detail) 1564
National Gallery, London
Enlarge on linked site
1567
The duke of Alba introduces a reign of terror in the Spanish Netherlands, by means of a tribunal known as the Council of Blood
1569
Flemish cartographer Gerardus Mercator publishes a map of the world, using the projection now known by his name
1572
Sea beggars seize the town of Brill and raise the flag of William of Orange (also known as William the Silent)
1573
William of Orange declares himself a Calvinist and assumes the leadership of the united provinces of the Netherlands
1573
The city of Alkmaar is saved when the Dutch breach their own dikes, threatening the Spanish troops with death by drowning
1576
The Pacification of Ghent unites all the provinces of the Netherlands in opposition to Spain
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