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| 1433 |
| | | Cosimo de' Medici, arrested by a rival faction, escapes with his life thanks to bribes and well-placed friends | |
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| 1434 |
| | | Giovanni Arnolfini, a merchant from Lucca trading in Bruges, commissions from van Eyck a portrait of himself and his wife | |
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| 1435 |
| | | Chancellor Nicolas Rolin, of Burgundy, commissions an altarpiece from Jan van Eyck | |
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| 1435 |
| | | Rogier van der Weyden, the third in the extraordinary trio of Flemish artists of the 1430s, is appointed painter to the city of Brussels | |
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| 1436 |
| | | Perspective fascinates Italian Renaissance painters after the publication of Alberti's treatise on the subject, De Pictura | |
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| 1438 |
| | | The Byzantine emperor John Palaeologus and the Patriarch of Constantinope, Joasaph, arrive in Ferrara to attend a council of the Roman Catholic church | |
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| 1439 |
| | | Florence acquires first-hand experience of Greek culture when Greek Orthodox priests join in a debate on theology, in particular the question of Filioque | |
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| 1439 |
| | | The Seventeenth Ecumenical Council moves from Ferrara, because of the danger of plague, and sets up in Florence | |
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| c. 1443 |
| | | The Dominican convent of San Marco, in Florence, is provided with a serenely beautiful series of frescoes by Fra Angelico and his assistants | |
|  | Fresco in San Marco Monastery
Fotofile CG
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| c. 1450 |
| | | Piero della Francesca paints masterpieces in his small home town of San Sepolcro | |
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