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| 363 |
| | | An apocryphal story states that Julian the Apostate, dying at Tarsus, acknowledges the victory of the Galilean, Jesus Christ | |
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| 367 |
| | | A document is distributed by the bishop of Alexandria, formally establishing the contents of the New Testament | |
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| c. 380 |
| | | The Codex Sinaiticus, the earliest surviving manuscript of the complete New Testament, is copied out - probably in Egypt | |
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| 386 |
| | | St Jerome settles in Bethlehem, where his holy women organize a monastery for his residence and a nearby convent for themselves | |
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| 390 |
| | | St Ambrose asserts the authority of the church, refusing communion to the emperor Theodosius in Milan until he does penance for a massacre | |
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| c. 400 |
| | | St Augustine reveals that as a young man, studying and teaching in Carthage, he often prayed for 'chastity and continence, but not yet' | |
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| c. 405 |
| | | St Jerome, in Bethlehem, completes the Latin translation of the Bible which later becomes known as the Vulgate | |
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| c. 413 |
| | | Prompted by the fall of Rome to the Visigoths, St Augustine undertakes a great work of Christian philosophy, the City of God | |
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| 431 |
| | | A council is convened at Ephesus to consider the theology of Nestorius, which is judged to be heretical | |
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| c. 450 |
| | | St Patrick creates a strong tradition of Celtic Christianity in Ireland, from his base in Armagh | |
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