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| 324 BC |
| | | When the army reaches Ecbatana, Hephaestion dies of a fever and the grief-stricken Alexander erects shrines in his memory | |
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| 323 BC |
| | | Alexander, still only 33, dies in Babylon following a banquet | |
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| from 323 BC |
| | | The spread of Greek rule by Alexander introduces the Hellenistic age, which will last for three centuries | |
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| 323 BC |
| | | Alexander's generals decide that the joint heirs to his throne shall be his half-brother (Philip III) and his posthumous son by Roxana (Alexander IV) | |
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| 323 BC |
| | | Real power will remain with the Macedonian generals, who after much dispute divide up Alexander's empire among themselves | |
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| 323 BC |
| | | In the carve up of Alexander the Great's empire, Ptolemy wins Egypt and founds the Ptolemaic dynasty – with himself as the pharaoh Ptolemy I | |
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| 323 BC |
| | | Ptolemy manages to acquire Alexander the Great's corpse, to lend authority to his rule in Egypt | |
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| 323 BC |
| | | Seleucus wins control of a vast area, comprising the eastern part of Alexander's empire from the Mediterranean to India | |
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| 322 BC |
| | | Alexander's corpse, hijacked by Ptolemy, becomes a sacred relic in Alexandria | |
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| 321 BC |
| | | Chandragupta Maurya seizes the throne of Magadha, in India, and establishes the Mauryan dynasty | |
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