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| 1816 |
| | | Henrietta Hotham dies and the Marble Hill estate is sold to Timothy Brent then living at Little Marble Hill. The house subsequently has a number of owners. | |
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| 1816 |
| | | Rossini's opera The Barber of Seville has its premiere in Rome | |
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| 1816 |
| | | Robert Finley, a US anti-slavery campaigner, founds the American Colonization Society to settle freed slaves in Africa | |
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| 1816 |
| | | Shaka wins control of the Zulu and begins to build them into a formidable military machine | |
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| 1816 |
| | | René Laënnec, reluctant to press his ear to the chest of a young female patient, finds a solution in the stethoscope | |
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| 1816 |
| | | The independence of Argentina is formally proclaimed, dropping any pretence of remaining loyal to the Spanish king | |
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| 1816 |
| | | The British establish Bathurst (now Banjul) at the mouth of the Gambia as a base against the slave trade | |
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| 1816 |
| | | Republican candidate James Monroe wins the US presidential election by a wide margin | |
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| 1816 |
| | | London's first iron bridge is completed at Vauxhall | |
|  | Vauxhall Bridge, 1820
Guildhall Library
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| 1817 |
| | | US poet William Cullen Bryant publishes Thanatopsis, written seven years previously at the age of 16 | |
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