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| | | World History timeline |
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| 1745 |
| | The principle of the Leyden jar is discovered by an amateur German physicist, Ewald Georg von Kleist, dean of the cathedral in Kamin | |
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| 1745 |
| | Charles Edward Stuart lands at Eriskay in the Hebrides, launching the Forty-Five Rebellion | |
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| 1745 |
| | Charles Edward Stuart gathers support for the Forty-Five Rebellion on his way south from the Hebrides and reaches Edinburgh | |
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| 1745 |
| | Charles Edward Stuart marches as far south as Derby, but then turns back | |
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| 1745 |
| | Frederick the Great's Prussian soldiers, advancing in shallow disciplined formation, outclass other armies of the time | |
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| 1745 |
| | Frederick II's three victories in 1745 cause him to be known by his contemporaries as Frederick the Great | |
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| 1746 |
| | Frederick the Great begins to build the summer palace of Sans Souci at Potsdam | |
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| 1746 |
| | Charles Edward Stuart and his 5000 Scots are routed at Culloden, bringing the Forty-Five Rebellion to an abrupt end | |
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| 1746 |
| | Tartan and Highland dress are banned by the British government, in a prohibition not lifted until 1782 | |
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| 1746 |
| | An earthquake destroys much of Lima, and an ensuing tidal wave engulfs its port at Callao | |
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| 1746 |
| | Monsieur Passemont constructs in Paris a millennium clock which can record the date in any year up to AD 9999 | |
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| 1746 |
| | French forces capture the British East India Company's fort of Madras | |
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| 1746 |
| | The French commander Maurice de Saxe succeeds in occupying the entire Austrian Netherlands | |
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| 1747 |
| | A tribal leader, Ahmad Shah Abdali, is elected king of the Afghans in an event seen as the foundation of the Aghan nation | |
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| 1747 |
| | Samuel Richardson's Clarissa begins the correspondence which grows into the longest novel in the English language | |
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| 1748 |
| | Systematic digging begins near Vesuvius, in an area where ancient fragments are often unearthed - soon discovered to be Pompeii | |
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| 1748 |
| | The treaty of Aix-la-Chapelle ends the War of the Austrian Succession, but only postpones the continuation of hostilities (in the Seven Years' War) | |
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| 1748 |
| | The peace treaty returns all captured territories to their owners – with the exception of Silesia, which becomes part of Prussia | |
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| 1749 |
| | A French official travels down the Ohio valley, placing markers to claim it for France | |
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| 1749 |
| | Henry Fielding introduces a character of lasting appeal in the lusty but good-hearted Tom Jones | |
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| 1749 |
| | Shortly before his death (in 1750) J.S. Bach completes his Mass in B Minor, worked on over many years | |
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| c. 1750 |
| | Naval engagements are now fought in lines of battle, with only the most heavily armed vessels rated as 'ships of the line' | |
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| 1750 |
| | Horace Walpole begins to create his own Strawberry Hill, a neo-Gothic fantasy, on the banks of the Thames west of London | |
| | Strawberry Hill admission ticket Richmond upon Thames Local Studies Collection
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| 1751 |
| | Robert Clive prevails over the French after holding out during the seven-week siege of Arcot in southern India | |
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| 1751 |
| | Giovanni Battista Tiepolo begins a series of frescoes to decorate the prince bishop's residence in Würzburg | |
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| 1751 |
| | A great French undertaking by Denis Diderot, his 28-volume Encyclopédie, begins publication | |
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